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This is a rare life threatening condition that occurs in genetically prone individuals when submitted to general anaesthesia.
- all volatile anaesthesia agents, especially halothane.
- most gas anasthesia
- the neuromuscular blocking agent succinylcholine.
- Genetic predisposition.
Characteristic signs are muscular rigidity, followed by metabolic speed up: increased oxygen consumption and carbon dioxide production, tachycardia (fast heart rate); and an increase in body temperature at a rate of up to ~2°C per hour.
Later on you can get rhabdomyolysis (breakdown of muscle tissue), with red-brown wee and evidence of electrolyte disturbances. The temperature of 58°C might be an issue too...
You probably won't have time to do much - you'll be too busy panicking, but the main tests is some kind of muscle biopsy. I suspect it won't come up in an exam.
Currently associated with a less than 10% mortality rate, and getting significantly better.