Respiratory failure
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Definition
PaO2<8kPa. There are two types which are defined based on the PaCO2.
Type I
PaCO2 is normal or low. Basically, hypoxia without hypercapnia (low oxygen, not high carbon dioxide). It doesn't matter if the CO2 is low or normal - if it's not high and the patient is hypoxic, it's type I respiratory failure.
Anything which causes a ventilation/perfusion (V/Q) mismatch can cause type I respiratory failure. V/Q mismatch is where the amount of air coming into the lungs (ventilation) is just enough to oxygenate the amount of blood coming into the lungs (perfusion).