SSRI: Difference between revisions
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The most important of these with regards to psychiatry are [[Depression|depression]] and, to lesser extent though still important [[Anxiety|anxiety]]. | The most important of these with regards to psychiatry are [[Depression|depression]] and, to lesser extent though still important [[Anxiety|anxiety]]. SSRIs are the first-line pharmocological treatment in both these conditions. | ||
==Contraindications== | ==Contraindications== | ||
Revision as of 16:14, 4 June 2008
Selective serotonin reuptake inhibitors are an antidepressants indicated in depression and anxiety.
Method Of Action
Depression and therefore SSRI action is not fully understood. There are a variety of theories on the neurophysiology of depression but one is that there's a lack of stimulation of neurons at the synapse. Serotonin is a neurotransmitter and SSRIs inhibit serotonin reuptake in the synaptic cleft, increasing stimulation of the post-synaptic neuron.
Indications
- Depression
- Anxiety - in the first 2 weeks, anxiety will increase with SSRI alone. So diazepam must be prescribed alongside
- Some personality disorders
- Premature ejaculation
The most important of these with regards to psychiatry are depression and, to lesser extent though still important anxiety. SSRIs are the first-line pharmocological treatment in both these conditions.