Barrett's oesophagus

An example of the discolouration of the bottom of the oesophagus seen by endoscopy.

Definition

A premalignant condition of the oesophagus, often precipitated by reflux.

Epidemiology

Present in about 10% of reflux sufferers, so pretty common. Probably there in about 1% of population.

Pathophysiology

It's lower oesophageal metaplasia, where the squamous cells become columnar. May convert to colonic or gastric cells – the colonic ones have a higher adenocarcinoma rate. It is considered a "premalignant" condition – one to be alert for. 10% of patients presenting with GO reflux have it.

Risk Factors

• Reflux

That's about it.

Clinical Features

None. It generally causes no symptoms other than that you get from having reflux itself. If you start getting dysphagia, start to worry!

Prognosis

On it's own, not really an issue