Bipolar disorder
Definition
A mood disorder, characterised by one episode of abnormally elevated mood (known as mania).
In current thought, bipolar is a condition where the patient will experience periods at opposite ends of a mood spectrum: high and low. It is thought that depression is where the patient only experiences one end of the spectrum, hence depression being known as unipolar.
Epidemiology
Lifetime prevalence is around 0.8%.
Pathophysiology
There is a stronger genetic link in bipolar than in any other non-organic mental disorder. Aside from this, a stressful life event is often a precipitating factor.
Risk Factors
- Family History of Bipolar or Depression
- Past Medical history of depression.
Clinical Features
Investigations
Management
Short-term
To treat an acute episode of mania, use an antipsychotic first-line because they are awesome. If the patient has previously had a good response to lithium or valproate, feel free to use those too - "if it ain't broke, don't fix it", I guess. Benzodiazepines can also be used to sedate the patient if they're being fidgety.
If they're being really bad, you can tranquilise them using olanzapine, lorazepam or haloperidol im.
Long-term
Use olanzapine, lithium or valproate. (An atypical antipsychotic, mood stabiliser and anticonvulsant, respectively). Psychological therapy and education will help.