Diuretics: Difference between revisions

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Get rid of water and used in [[oedema]] (reduces excess water) and [[hypertension]] (reduces fluid and thus pressure in [[circulation]]).
Commonly used [[cardiac drugs]]. They get rid of water and used in [[oedema]] (reduces excess water) and [[hypertension]] (reduces fluid and thus pressure in [[circulation]]).
===Loop===
===Loop===
'''Furosemide''' acts on a Na-K symporter (kicks out K<sup>+</sup>, reabsorbs Na<sup>+</sup>). Thus [[hypokalaemia]] is a side-effect
'''Furosemide''' acts on a Na-K symporter (kicks out K<sup>+</sup>, reabsorbs Na<sup>+</sup>). Thus [[hypokalaemia]] is a side-effect
===Thiazide===
===Thiazide===
'''Bendroflumethiazide''' prevents Na<sup>+</sup> reabsorption. Thus [[hyponatraemia]] is a side-effect.
'''Bendroflumethiazide''' prevents Na<sup>+</sup> reabsorption. Thus [[hyponatraemia]] is a side-effect. And they can gain calcium, causing [[hypercalcaemia]].
 
===Potassium-sparing===
===Potassium-sparing===
'''Spironolactone'''. Seems to be pretty awesome. Probably expensive or something.
'''Spironolactone'''. Seems to be pretty awesome. Gains K<sup>+</sup> so [[hyperkalaemia]] is a potential side-effect. Works by inhibiting [[aldosterone]].

Latest revision as of 18:40, 3 June 2010

Commonly used cardiac drugs. They get rid of water and used in oedema (reduces excess water) and hypertension (reduces fluid and thus pressure in circulation).

Loop

Furosemide acts on a Na-K symporter (kicks out K+, reabsorbs Na+). Thus hypokalaemia is a side-effect

Thiazide

Bendroflumethiazide prevents Na+ reabsorption. Thus hyponatraemia is a side-effect. And they can gain calcium, causing hypercalcaemia.

Potassium-sparing

Spironolactone. Seems to be pretty awesome. Gains K+ so hyperkalaemia is a potential side-effect. Works by inhibiting aldosterone.