Diuretics: Difference between revisions
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Commonly used [[cardiac drugs]]. They get rid of water and used in [[oedema]] (reduces excess water) and [[hypertension]] (reduces fluid and thus pressure in [[circulation]]). | |||
===Loop=== | ===Loop=== | ||
'''Furosemide''' acts on a Na-K symporter (kicks out K<sup>+</sup>, reabsorbs Na<sup>+</sup>). Thus [[hypokalaemia]] is a side-effect | '''Furosemide''' acts on a Na-K symporter (kicks out K<sup>+</sup>, reabsorbs Na<sup>+</sup>). Thus [[hypokalaemia]] is a side-effect | ||
===Thiazide=== | ===Thiazide=== | ||
'''Bendroflumethiazide''' prevents Na<sup>+</sup> reabsorption. Thus [[hyponatraemia]] is a side-effect. | '''Bendroflumethiazide''' prevents Na<sup>+</sup> reabsorption. Thus [[hyponatraemia]] is a side-effect. And they can gain calcium, causing [[hypercalcaemia]]. | ||
===Potassium-sparing=== | ===Potassium-sparing=== | ||
'''Spironolactone'''. Seems to be pretty awesome. | '''Spironolactone'''. Seems to be pretty awesome. Gains K<sup>+</sup> so [[hyperkalaemia]] is a potential side-effect. Works by inhibiting [[aldosterone]]. |
Latest revision as of 18:40, 3 June 2010
Commonly used cardiac drugs. They get rid of water and used in oedema (reduces excess water) and hypertension (reduces fluid and thus pressure in circulation).
Loop
Furosemide acts on a Na-K symporter (kicks out K+, reabsorbs Na+). Thus hypokalaemia is a side-effect
Thiazide
Bendroflumethiazide prevents Na+ reabsorption. Thus hyponatraemia is a side-effect. And they can gain calcium, causing hypercalcaemia.
Potassium-sparing
Spironolactone. Seems to be pretty awesome. Gains K+ so hyperkalaemia is a potential side-effect. Works by inhibiting aldosterone.