Antibiotics - nucleic acid synthesis inhibitors
(Redirected from Metronidazole)
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For others, go to our page on antibiotics.
Quinolones
Sulphonamides
Rifampicin
Trimethoprim
Metronidazole
It is a bactericidal agent. It is metabolised to a toxic intermediate not found in eukaryotic cells. This intermediate inhibits bacterial cell DNA synthesis and degrades exisitng DNA.
It has antibacterial properties against anaerobic bacteria and also protozoa. It an be given orally, via IV, as a topical agent or per rectum. It should not be given to pregnant women.
Side effects include GI disturbances, headache. A severe reaction will occur if taken with alcohol.